Processed Tomato Products as a Source of Dietary Lycopene: Bioavailability and Antioxidant Properties

Publication: Canadian Journal of Dietetic Practice and Research
December 2004

Abstract

Oxidative stress is one of the major contributors to increased risk of chronic diseases. A diet rich in tomatoes and tomato products containing lycopene, a carotenoid antioxidant, has been found to protect against these chronic diseases by mitigating oxidative damage. The study aim was to evaluate the effects of a long-term tomato-rich diet, consisting of various processed tomato products, on bioavailability and antioxidant properties of lycopene. Seventeen healthy human subjects (ten men, seven non-pregnant women) participated in the study. Following a two-week washout period during which subjects avoided foods containing lycopene, all subjects consumed test tomato products including tomato juice, tomato sauce, tomato paste, ketchup, spaghetti sauce, and ready-to-serve tomato soup providing 30 mg of lycopene a day for four weeks. At the end of treatment, serum lycopene level increased significantly (p <0.05), from 181.79 ± 31.25 to 684.7 ± 113.91 nmol/L. Similarly, total antioxidant potential increased significantly (p <0.05), from 2.26 ± 0.015 to 2.38 ± 0.17 mmol/L Trolox equivalent. Lipid and protein oxidation was reduced significantly (p <0.05). The results suggest that a tomato-rich diet containing different sources of lycopene can increase serum lycopene levels and reduce oxidative stress effectively.

Résumé

Le stress oxydatif est l'un des principaux facteurs qui contribuent à accroître le risque de maladies chroniques. Des recherches ont montré qu'une alimentation riche en tomates et en produits de la tomate qui renferment du lycopène, antioxydant caroténoïde, apporte une protection contre les maladies chroniques en atténuant le dommage oxydatif. Le but de cette étude était d’évaluer les effets d'une alimentation à long terme riche en tomates, renfermant divers produits de transformation de la tomate, sur la biodisponibilité et les propriétés antioxydantes du lycopène. Les participants de l’étude étaient 17 sujets humains en bonne santé (10 hommes, 7 femmes non-enceintes). Après une période de deux semaines d’élimination pendant lesquelles les sujets évitaient les aliments renfermant du lycopène, tous les sujets ont consommé des produits de la tomate, notamment du jus de tomate, de la sauce tomate, de la pâte de tomate, du ketchup, de la sauce à spaghetti et de la soupe aux tomates prête à servir, fournissant 30 mg de lycopène par jour pendant quatre semaines. Au terme du traitement, la concentration de lycopène sérique avait augmenté de façon significative (p<0,05), passant de 181,79±31,25 à 684,7±113,91 nmol/L. De même, le potentiel antioxydant total a augmenté de façon significative (p<0,05), passant de 2,26±0,015 à 2,38±0,17 mmol/L d’équivalent Trolox. L'oxydation des lipides et des protéines a diminué de façon significative (p<0,05). Les résultats incitent à penser qu'une alimentation riche en tomates renfermant diverses sources de lycopène peut accroître les concentrations de lycopène sérique et réduire le stress oxydatif de manière efficace.

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Published In

cover image Canadian Journal of Dietetic Practice and Research
Canadian Journal of Dietetic Practice and Research
Volume 65Number 4December 2004
Pages: 161 - 165

History

Version of record online: 12 February 2007

Authors

Affiliations

A. Venket Rao, PhD
Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, ON

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